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Danielle Vahala

Research Profile

Investigating cellular mechanisms involved in cancer metastasis and whether this is a matrix-driven response. Integrins play a vital role in focal adhesion formation and transduce mechanical input to the nucleus to alter downstream cellular processes.

Danielle Vahala

Cancer cells, through all stages of metastasis, experience vastly different microenvironments and subsequently display differing degrees of adhesion. The aim of my research is to investigate the mechanisms by which integrin-ligand interactions are regulating cancer cell adhesion and thus determine whether this is a driver for metastasis.

Supervisors

A/Prof Yu Suk Choi, Prof Brendan Kennedy

Contact

Keywords: Cancer | Mechanobiology

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