Natasha Dale
Research Profile
Natasha Dale was a PhD candidate at the Harry Perkins Institute of Medical Research and UWA Centre for Medical Research. Natasha’s PhD focused on elucidating how G protein-coupled receptors (GPCRs) transduce intracellular signals and traffic through the cell upon agonist binding, with a particular focus on the orexin receptor system.
Better understanding of these processes can assist in the design of new drugs with improved efficacy and specificity. To achieve this, cutting-edge Bioluminescence Resonance Energy Transfer (BRET) techniques are being developed and implemented.
Alongside her PhD research, Natasha was actively engaged with industry, completing a 4-month APR Internship with biopharmaceutical company Dimerix in 2019-2020, as well as completing the Perth Biodesign for Medtech course in 2020-2021.
Natasha also took on multiple leadership roles as Chair of the Perkins Student Committee (2021), ASCEPT Drug Discovery Student Representative (2017-2021) and a founding member of the QEII Research Student Network (2020-2021).
Supervisors
Professor Kevin Pfleger, Dr Liz Johnstone
Contact
Keywords: GPCR pharmacology | BRET assay techniques | CNS receptor pharmacology