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Jiayue (Leo) Li

Research Profile

Jiayue (Leo) Li was a PhD candidate in the School of Engineering at the University of Western Australia (UWA) and the Harry Perkins Institute of Medical Research. He was the recipient of the Industrial Transformation Training Centre (ITTC) PhD Scholarship and the Science Industry PhD Fellowship in 2019. Leo’s PhD focused on developing novel high-resolution optical imaging techniques for the measurement of cell and tissue mechanics.

The mechanical properties of tissue, across different length scales, play an important role in determining its function. On the cellular scale, cells sense the surrounding microenvironment through mechanotransduction that modulates cell function and is important in tissue development. On the tissue scale, alterations to the mechanical properties of tissue are correlated with the pathogenesis of many diseases, such as cancer. Thus, imaging the mechanical properties of tissue from the cellular to tissue scales is vital to improving our understanding of disease towards developing new treatments and targeted therapies.

 

Before embarking on his PhD, Leo earned a Master of Mechanical Engineering from UWA and graduated with First-Class Honours in Mechanical Engineering from Technological University Dublin, Ireland. He is a Postdoctoral Research Associate in BRITElab at the Harry Perkins Institute of Medical Research, where his current research is centred on developing a new multi-parametric imaging technique for breast tumour margin assessment.

Supervisors

Prof Brendan Kennedy, Dr Alireza Mowla, and Prof Minghao Zheng

Contact

Keywords: Biomechanics | Mechanobiology | Biomedical imaging | Optical Coherence Elastography

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